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![Plla Hyaluronic Acid Filler]()
Plla Hyaluronic Acid FillerPlla Hyaluronic Acid Filler1,Customization:Available OEM/ODM2,Model NO.： 1ml derm/deep3,Certification: ISO, CE, FDA 4,Disinfection: Disinfection5,Packing: 1 Syringe/Box6,Color： Transparent7,Syringe
Your Professional Plla Filler Supplier!
BEUFILLER is a leading manufacturer, marketer, and distributor of premium aesthetic medical products. Our core offerings encompass hyaluronic acid dermal fillers, , mesotherapy solutions for various applications such as fat reduction, skin whitening, hair growth, anti-melanogenesis, and anti-aging treatments, as well as PDO Threads.
Why Choose Us
Rich experience
With over two decades of expertise in the medical aesthetics sector, With over 110 staff, including 5 industry experts and 6 international designers, BEUFILLER caters to diverse global market needs.
Production Equipment
Our state-of-the-art facilities include three GMP-certified production lines and a Class 100 pharmaceutical cleanroom, enabling us to achieve a monthly production capacity of 500,000 units.
Our Certifications
Certified by CE, MDSAP, and GMP, BEUFILLER adheres to CFDA and EU MDD standards, ensuring safety, innovation, and customer satisfaction.
Overview Of Plla Filler
Poly-L-lactic acid (PLLA) is an absorbable, semi-permanent, injectable implant that can restore volume and gradually stimulate collagen formation. Poly-L-lactic acid is FDA-approved for correcting facial fat loss associated with antiretroviral therapy-induced lipoatrophy in HIV patients.
Product Specification
We offer the following Specifications
|
Product Name |
BEUFILLER PLLA Hyaluronic Acid Filler Anti Wrinkles |
|
Type |
Rveiling Lines 1ML |
|
Needle |
27G |
|
Treatment Areas |
It should be used by an authorized practitioner. Do not re-sterilize or mix with other products. |
|
Injection Depth |
Mid to Deep Dermis |
|
Duration |
24 months |
Advantages of PLLA Filler
Long-Lasting Results
The effects of PLLA can persist for up to 24 months.
Natural-Looking Outcomes
Gradual collagen stimulation ensures subtle and natural enhancements.
Safety and Biodegradability
PLLA is absorbed by the body over time, reducing the risk of complications.
There are three main layers involved, here:
- Deep reticular dermis
- Subcutaneous tissue
- Supraperiosteal layer
As your goal in using these biostimulators is to stimulate collagen down in the deeper layers of the face, you'll generally be injecting into the deep reticular dermis and subcutaneous tissue.
The deep reticular dermis - the lower layer of the dermis - is where collagen and elastin fibres are found. By injecting PLLA here, you can effectively stimulate new collagen production.
We inject PLLA into the subcutaneous tissue, beneath the dermis, to restore volume loss.
In some cases, you can inject into the supraperiosteal layer which sits above the bone. This is for treating specific areas, such as the temples or cheekbones, to achieve more significant volume restoration.
Composition And Mechanism Of Action
PLLA is a biocompatible, biodegradable, high molecular weight synthetic polymer of L-lactic acid. PLLA is the only resorbable filler currently on the market which is approved by the FDA to last up to 25 months (the cut off time in the initial HIV study used to gain initial FDA approval). The longevity is due to the slow degradation kinetics of this high molecular weight polymer.
Product is supplied in a glass vial containing a lyophilized powder of PLLA microparticles along with sodium carboxymethylcellulose (CMC-a suspending agent used to maintain even distribution), and mannitol (to enhance solubility). Prior to use, the product is reconstituted with 5mL sterile water for injection (SWFI) to form a suspension, which is then left to "hydrate” for at least 2 hours as per the current FDA approved label.
The prevailing theory of the mechanism of action of PLLA is that upon injection, it stimulates a subclinical inflammatory response, followed by encapsulation of the particles, and subsequent fibroblast proliferation and collagen formation. 10,11Some suggest that the product may upregulate the production of collagen by other pathways as well.
Once the carrier solution is reabsorbed, a slow process of biodegradation of the microspheres occurs consisting of hydration, loss of cohesion and molecular weight, solubilization, and phagocytosis of small fragments of PLLA by the host's macrophages. PLLA is eventually degraded into lactic acid which is eliminated as CO2 and H2O through the respiratory system.
Packaging And Delivery
One syringe and two needles of BD in a PVC Blister, One Blister and instruction in a retail box.
Certificate
● ISO 9001 ● ISO 13485 ● CE 2460 ● MDSAP
FAQ
We're well-known as one of the leading plla filler manufacturers in China. If you're going to wholesale high quality plla filler made in China, welcome to get more information from our factory.
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